# Surfactant Positive Airway Pressure and Pulse Oximetry Trial

> **NCT00233324** · PHASE3 · COMPLETED · sponsor: **NICHD Neonatal Research Network** · enrollment: 1316 (actual)

## Conditions studied

- Infant, Newborn, Diseases
- Other Preterm Infants
- Infant, Small for Gestational Age
- Premature Birth
- Bronchopulmonary Dysplasia
- Retinopathy of Prematurity

## Interventions

- **DRUG:** Surfactant
- **DEVICE:** Continuous Positive Airway Pressure (CPAP)
- **DRUG:** Supplemental oxygen with target saturation of 85 to 89%
- **DRUG:** Supplemental oxygen with target saturation of 91 to 95%

## Key facts

- **NCT ID:** NCT00233324
- **Lead sponsor:** NICHD Neonatal Research Network
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-02
- **Primary completion:** 2009-02
- **Final completion:** 2016-08
- **Target enrollment:** 1316 (ACTUAL)
- **Last updated:** 2019-04-18

## Collaborators

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- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00233324

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00233324, "Surfactant Positive Airway Pressure and Pulse Oximetry Trial". Retrieved via MORVS 2026-10-17 from https://api.morvs.ai/clinical/NCT00233324. Licensed CC0.

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