Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma
Conditions
- Anaplastic Medulloblastoma
- Medulloblastoma
- Supratentorial Embryonal Tumor, Not Otherwise Specified
- Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions
- PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation
- DRUG: Carboplatin
- DRUG: Cisplatin
- DRUG: Cyclophosphamide
- DRUG: Etoposide
- BIOLOGICAL: Filgrastim
- OTHER: Laboratory Biomarker Analysis
- DRUG: Leucovorin Calcium
- DRUG: Methotrexate
- OTHER: Quality-of-Life Assessment
- DRUG: Thiotepa
- DRUG: Vincristine Sulfate
Sponsor
Children's Oncology Group
Collaborators