Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer

NCT00551421 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

COMPLETED

Status

17

Enrollment

NIH

Sponsor class

Conditions

Adenocarcinoma of the Colon
Adenocarcinoma of the Rectum
Recurrent Colon Cancer
Recurrent Rectal Cancer
Stage III Colon Cancer
Stage III Rectal Cancer
Stage IV Colon Cancer
Stage IV Rectal Cancer

Interventions

BIOLOGICAL: pertuzumab
BIOLOGICAL: cetuximab
DRUG: irinotecan hydrochloride
OTHER: immunohistochemistry staining method
OTHER: fluorescence in situ hybridization
OTHER: gene expression analysis
OTHER: mutation analysis
OTHER: polymerase chain reaction
OTHER: laboratory biomarker analysis

Sponsor

National Cancer Institute (NCI)