Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma
Conditions
- Localized Resectable Neuroblastoma
- Localized Unresectable Neuroblastoma
- Recurrent Neuroblastoma
- Regional Neuroblastoma
- Stage 4 Neuroblastoma
- Stage 4S Neuroblastoma
Interventions
- PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation
- DRUG: Carboplatin
- DRUG: Cisplatin
- DRUG: Cyclophosphamide
- DRUG: Doxorubicin Hydrochloride
- DRUG: Etoposide
- RADIATION: External Beam Radiation Therapy
- BIOLOGICAL: Filgrastim
- DRUG: Isotretinoin
- OTHER: Laboratory Biomarker Analysis
- DRUG: Melphalan
- PROCEDURE: Peripheral Blood Stem Cell Transplantation
- OTHER: Pharmacological Study
- DRUG: Thiotepa
- DRUG: Topotecan Hydrochloride
- DRUG: Vincristine Sulfate Liposome
Sponsor
Children's Oncology Group
Collaborators