Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

NCT01051557 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

COMPLETED

Status

36

Enrollment

NIH

Sponsor class

Conditions

Adult Anaplastic Astrocytoma
Adult Anaplastic Oligodendroglioma
Adult Diffuse Astrocytoma
Adult Giant Cell Glioblastoma
Adult Glioblastoma
Adult Gliosarcoma
Adult Mixed Glioma
Adult Oligodendroglioma
Recurrent Adult Brain Neoplasm

Interventions

OTHER: Laboratory Biomarker Analysis
DRUG: Perifosine
DRUG: Temsirolimus
PROCEDURE: Therapeutic Conventional Surgery

Sponsor

National Cancer Institute (NCI)