Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects

NCT01596777 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

15

Enrollment

OTHER

Sponsor class

Conditions

Intestinal Obstruction

Interventions

DRUG: Loperamide
DRUG: Loperamide placebo
DRUG: Methylnaltrexone placebo
DRUG: Methylnaltrexone 12 mg sc.
DRUG: Methylnaltrexone IR capsule
DRUG: Methylnaltrexone ER capsule
DEVICE: Colon Transit
DRUG: Sulfasalazine

Sponsor

University Medicine Greifswald