# Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

> **NCT01652196** · PHASE2 · COMPLETED · sponsor: **John Hays** · enrollment: 56 (actual)

## Conditions studied

- Mucinous Adenocarcinoma of the Colon
- Mucinous Adenocarcinoma of the Rectum
- Signet Ring Adenocarcinoma of the Colon
- Signet Ring Adenocarcinoma of the Rectum
- Stage IV Colon Cancer
- Stage IV Rectal Cancer

## Interventions

- **BIOLOGICAL:** aflibercept
- **DRUG:** oxaliplatin
- **DRUG:** leucovorin
- **DRUG:** fluorouracil
- **OTHER:** Correlative Studies
- **PROCEDURE:** DCE MRI
- **RADIATION:** f18FDG-PET
- **PROCEDURE:** PET (positron emission tomography)

## Key facts

- **NCT ID:** NCT01652196
- **Lead sponsor:** John Hays
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-11-14
- **Primary completion:** 2019-08-06
- **Final completion:** 2022-08-30
- **Target enrollment:** 56 (ACTUAL)
- **Last updated:** 2025-02-05

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01652196

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01652196, "Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer". Retrieved via MORVS 2026-11-02 from https://api.morvs.ai/clinical/NCT01652196. Licensed CC0.

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