Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

NCT02194738 · clinicaltrials.gov ↗

NA

Phase

ACTIVE_NOT_RECRUITING

Status

8300

Enrollment

NIH

Sponsor class

Conditions

Stage IB Lung Non-Small Cell Carcinoma AJCC v7
Stage II Lung Non-Small Cell Cancer AJCC v7
Stage IIA Lung Cancer AJCC v8
Stage IIB Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIA Lung Non-Small Cell Cancer AJCC v7
Stage IIIB Lung Cancer AJCC v8

Interventions

PROCEDURE: Biospecimen Collection
DRUG: Carboplatin
DRUG: Cisplatin
OTHER: Clinical Observation
PROCEDURE: Computed Tomography
DRUG: Crizotinib
OTHER: Cytology Specimen Collection Procedure
PROCEDURE: Echocardiography Test
DRUG: Erlotinib
DRUG: Gemcitabine Hydrochloride
BIOLOGICAL: Nivolumab
DRUG: Paclitaxel
BIOLOGICAL: Pembrolizumab
DRUG: Pemetrexed
DRUG: Pemetrexed Disodium
OTHER: Placebo Administration
PROCEDURE: Positron Emission Tomography

Sponsor

National Cancer Institute (NCI)