# PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes

> **NCT02282423** · NA · TERMINATED · sponsor: **Mayo Clinic** · enrollment: 26 (actual)

## Conditions studied

- Diabetes
- Obesity

## Interventions

- **BEHAVIORAL:** Pre-study dietary and exercise instruction.
- **PROCEDURE:** Screening examination and oral glucose tolerance test
- **PROCEDURE:** Euglycemic clamp
- **PROCEDURE:** VO2max.
- **BEHAVIORAL:** Acute exercise bout
- **PROCEDURE:** Percutaneous needle muscle biopsies

## Key facts

- **NCT ID:** NCT02282423
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2014-05
- **Primary completion:** 2016-04
- **Final completion:** 2016-04
- **Target enrollment:** 26 (ACTUAL)
- **Why stopped:** PI job change
- **Last updated:** 2016-05-12

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02282423

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02282423, "PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes". Retrieved via MORVS 2026-10-18 from https://api.morvs.ai/clinical/NCT02282423. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*