Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast Cancer

NCT02689427 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

24

Enrollment

OTHER

Sponsor class

Conditions

Invasive Breast Carcinoma
Stage I Breast Cancer AJCC v7
Stage IA Breast Cancer AJCC v7
Stage IB Breast Cancer AJCC v7
Stage II Breast Cancer AJCC v6 and v7
Stage IIA Breast Cancer AJCC v6 and v7
Stage IIB Breast Cancer AJCC v6 and v7
Stage III Breast Cancer AJCC v7
Stage IIIA Breast Cancer AJCC v7
Stage IIIB Breast Cancer AJCC v7
Stage IIIC Breast Cancer AJCC v7
Triple-Negative Breast Carcinoma

Interventions

PROCEDURE: Axillary Lymph Node Dissection
DRUG: Enzalutamide
OTHER: Laboratory Biomarker Analysis
PROCEDURE: Lymph Node Biopsy
DRUG: Paclitaxel
PROCEDURE: Therapeutic Conventional Surgery

Sponsor

M.D. Anderson Cancer Center

Collaborators

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