Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

NCT02750254 · clinicaltrials.gov ↗

PHASE1

Phase

TERMINATED

Status

5

Enrollment

OTHER

Sponsor class

Stopped Toxicity. Only enrolled patients in phase I portion of trial.

Conditions

Acute Myeloid Leukemia
Myelodysplastic Syndrome
Acute Lymphocytic Leukemia

Interventions

DRUG: Fludarabine
RADIATION: Fractionated total body irradiation
DRUG: Busulfan
DRUG: Cyclophosphamide
RADIATION: Single dose total body irradiation
DRUG: Melphalan
DRUG: Granulocyte-colony stimulating factor
PROCEDURE: Stem cell transplant
DRUG: Azacitidine

Sponsor

Washington University School of Medicine