# Pilot Study of the Effect of Trastuzumab and GM-CSF on Children With Recurrent Ependymoma

> **NCT02774421** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **University of Colorado, Denver** · enrollment: 33 (estimated)

## Conditions studied

- Posterior Fossa Ependymoma (PFEPN)

## Interventions

- **DRUG:** Trastuzumab after SubQ GM-CSF
- **DRUG:** Trastuzumab in combination with SubQ GM-CSF

## Key facts

- **NCT ID:** NCT02774421
- **Lead sponsor:** University of Colorado, Denver
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2017-06-12
- **Primary completion:** 2025-02-27
- **Final completion:** 2027-03
- **Target enrollment:** 33 (ESTIMATED)
- **Last updated:** 2026-04-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02774421

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02774421, "Pilot Study of the Effect of Trastuzumab and GM-CSF on Children With Recurrent Ependymoma". Retrieved via MORVS 2026-11-03 from https://api.morvs.ai/clinical/NCT02774421. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*