Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

NCT03244384 · clinicaltrials.gov ↗

PHASE3

Phase

ACTIVE_NOT_RECRUITING

Status

739

Enrollment

NIH

Sponsor class

Conditions

Localized Renal Pelvis and Ureter Urothelial Carcinoma
Locally Advanced Bladder Urothelial Carcinoma
Locally Advanced Renal Pelvis and Ureter Urothelial Carcinoma
Locally Advanced Ureter Urothelial Carcinoma
Locally Advanced Urothelial Carcinoma
Stage II Bladder Urothelial Carcinoma AJCC v6 and v7
Stage II Renal Pelvis and Ureter Cancer AJCC v7
Stage II Ureter Cancer AJCC v7
Stage III Bladder Urothelial Carcinoma AJCC v6 and v7
Stage III Renal Pelvis and Ureter Cancer AJCC v7
Stage III Ureter Cancer AJCC v7

Interventions

PROCEDURE: Biospecimen Collection
OTHER: Clinical Observation
PROCEDURE: Computed Tomography
PROCEDURE: CT Urography
PROCEDURE: Cystoscopy
PROCEDURE: Magnetic Resonance Imaging
BIOLOGICAL: Pembrolizumab
OTHER: Pharmacological Study
OTHER: Quality-of-Life Assessment
OTHER: Questionnaire Administration

Sponsor

National Cancer Institute (NCI)