A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

NCT03355794 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

19

Enrollment

OTHER

Sponsor class

Conditions

Diffuse Intrinsic Pontine Glioma
Malignant Glioma of Brain
High Grade Glioma
Bithalamic High Grade Glioma
Brainstem Glioma
Glioblastoma
Anaplastic Astrocytoma

Interventions

DRUG: ribociclib
DRUG: Everolimus

Sponsor

Children's Hospital Medical Center, Cincinnati

Collaborators

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