Low-Intensity Chemotherapy and Venetoclax in Treating Patients With Relapsed or Refractory B- or T-Cell Acute Lymphoblastic Leukemia

NCT03808610 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

TERMINATED

Status

53

Enrollment

OTHER

Sponsor class

Stopped \<75% participation

Conditions

Recurrent B Acute Lymphoblastic Leukemia
Recurrent T Acute Lymphoblastic Leukemia
Refractory B Acute Lymphoblastic Leukemia
Refractory T Acute Lymphoblastic Leukemia

Interventions

DRUG: Cyclophosphamide
DRUG: Cytarabine
DRUG: Dexamethasone
DRUG: Methotrexate
DRUG: Nelarabine
DRUG: Pegaspargase
DRUG: Prednisone
BIOLOGICAL: Rituximab
DRUG: Venetoclax
DRUG: Vincristine

Sponsor

M.D. Anderson Cancer Center

Collaborators

National Cancer Institute (NCI)