Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

NCT03811015 · clinicaltrials.gov ↗

PHASE3

Phase

ACTIVE_NOT_RECRUITING

Status

636

Enrollment

NIH

Sponsor class

Conditions

Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Interventions

PROCEDURE: Biospecimen Collection
DRUG: Cisplatin
PROCEDURE: Computed Tomography
PROCEDURE: Echocardiography Test
OTHER: Fludeoxyglucose F-18
RADIATION: Intensity-Modulated Radiation Therapy
BIOLOGICAL: Nivolumab
OTHER: Patient Observation
PROCEDURE: Positron Emission Tomography

Sponsor

National Cancer Institute (NCI)