Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

NCT04216329 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

11

Enrollment

NIH

Sponsor class

Conditions

Gliosarcoma
Newly Diagnosed
Glioblastoma

Interventions

DRUG: Selinexor
DRUG: Temozolomide
RADIATION: Generic Radiation therapy (RT)
OTHER: Selective serotonin receptor (5-HT3) antagonists
OTHER: Olanzapine
DIETARY_SUPPLEMENT: Salt tablets
OTHER: Anti-diarrheal

Sponsor

National Cancer Institute (NCI)