Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer

NCT04310007 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

117

Enrollment

NIH

Sponsor class

Conditions

Metastatic Lung Non-Squamous Non-Small Cell Carcinoma
Recurrent Lung Non-Squamous Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8

Interventions

PROCEDURE: Biospecimen Collection
DRUG: Cabozantinib S-malate
PROCEDURE: Computed Tomography
DRUG: Docetaxel
PROCEDURE: Echocardiography Test
DRUG: Gemcitabine Hydrochloride
DRUG: Nab-paclitaxel
BIOLOGICAL: Nivolumab
DRUG: Paclitaxel
BIOLOGICAL: Ramucirumab

Sponsor

National Cancer Institute (NCI)