A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478

Stopped Based on interim analysis, the Sponsor decided to terminate the study prematurely.

Conditions

• Healthy

Interventions

• DRUG: ACT-541478 10 mg
• DRUG: ACT-541478 30 mg
• DRUG: ACT-541478 100 mg
• DRUG: ACT-541478 300 mg
• DRUG: ACT-541478 1000 mg
• DRUG: ACT-541478 high or low dose (or placebo)
• DRUG: ACT-541478 dose E1
• DRUG: Matching placebo

Sponsor

Idorsia Pharmaceuticals Ltd.