# COSIMA: COronary SInus Reducer for the Treatment of Refractory Microvascular Angina

> **NCT04606459** · NA · RECRUITING · sponsor: **Johannes Gutenberg University Mainz** · enrollment: 144 (estimated)

## Conditions studied

- Coronary Microvascular Disease
- Refractory Angina

## Interventions

- **DEVICE:** Coronary sinus reducer
- **OTHER:** Optimal medical therapy

## Key facts

- **NCT ID:** NCT04606459
- **Lead sponsor:** Johannes Gutenberg University Mainz
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-04-01
- **Primary completion:** 2025-10-20
- **Final completion:** 2029-10-20
- **Target enrollment:** 144 (ESTIMATED)
- **Last updated:** 2023-09-28

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04606459

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04606459, "COSIMA: COronary SInus Reducer for the Treatment of Refractory Microvascular Angina". Retrieved via MORVS 2026-11-02 from https://api.morvs.ai/clinical/NCT04606459. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*