Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

NCT05198830 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

42

Enrollment

NIH

Sponsor class

Conditions

Lung Adenocarcinoma
Lung Large Cell Carcinoma
Lung Non-Squamous Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8

Interventions

DRUG: Carboplatin
DRUG: Cisplatin
PROCEDURE: Computed Tomography
BIOLOGICAL: Durvalumab
PROCEDURE: FDG-Positron Emission Tomography
PROCEDURE: Magnetic Resonance Imaging
DRUG: Methoxyamine
DRUG: Pemetrexed
RADIATION: Radiation Therapy

Sponsor

National Cancer Institute (NCI)