Testing Obeticholic Acid for Familial Adenomatous Polyposis

NCT05223036 · clinicaltrials.gov ↗

PHASE2

Phase

TERMINATED

Status

15

Enrollment

NIH

Sponsor class

Stopped Protocol has been completed prematurely due to poor accrual and study feasibility.

Conditions

Attenuated Familial Adenomatous Polyposis
Colorectal Carcinoma
Duodenal Carcinoma
Familial Adenomatous Polyposis

Interventions

PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
PROCEDURE: Gastrointestinal Endoscopy
BIOLOGICAL: Obeticholic Acid
DRUG: Placebo Administration
OTHER: Questionnaire Administration

Sponsor

National Cancer Institute (NCI)