# Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking

> **NCT05385055** · — · COMPLETED · sponsor: **Philip Morris Products S.A.** · enrollment: 974 (actual)

## Conditions studied

- Inflammation
- Oxidative Stress
- Smoking
- Smoking Abstinence

## Interventions

- **OTHER:** THS use
- **OTHER:** Cigarette smoking
- **OTHER:** Smoking abstinence

## Key facts

- **NCT ID:** NCT05385055
- **Lead sponsor:** Philip Morris Products S.A.
- **Sponsor class:** INDUSTRY
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2022-06-13
- **Primary completion:** 2023-12-27
- **Final completion:** 2024-04-23
- **Target enrollment:** 974 (ACTUAL)
- **Last updated:** 2026-05-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05385055

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05385055, "Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking". Retrieved via MORVS 2026-10-17 from https://api.morvs.ai/clinical/NCT05385055. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*