Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome

NCT05419011 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

186

Enrollment

NIH

Sponsor class

Conditions

Colorectal Carcinoma
Colorectal Neoplasm
Lynch Syndrome

Interventions

BIOLOGICAL: Adenovirus 5 CEA/MUC1/Brachyury Vaccine Tri-Ad5
PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
PROCEDURE: Colonoscopy
DRUG: Nogapendekin Alfa
DRUG: Placebo Administration
OTHER: Questionnaire Administration

Sponsor

National Cancer Institute (NCI)