A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella and Typhoid Fever

Conditions

• Salmonella Infections

Interventions

• BIOLOGICAL: Invasive nontyphoidal Salmonella-typhoid conjugate vaccine (iNTS-TCV) low dose
• BIOLOGICAL: Invasive nontyphoidal Salmonella-generalized modules for membrane antigens vaccine (iNTS-GMMA) low dose
• BIOLOGICAL: Typhoid conjugate vaccine (TCV) low dose
• BIOLOGICAL: Invasive nontyphoidal Salmonella-typhoid conjugate vaccine (iNTS-TCV) full dose
• BIOLOGICAL: Invasive nontyphoidal Salmonella-generalized modules for membrane antigens vaccine (iNTS-GMMA) full dose
• BIOLOGICAL: Typhoid conjugate vaccine (TCV) full dose
• BIOLOGICAL: GSK's Meningococcal A, C, Y and W-135 conjugate vaccine
• COMBINATION_PRODUCT: GSK's Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine
• COMBINATION_PRODUCT: Sanofi Pasteur's Typhoid Vi polysaccharide vaccine
• DRUG: Placebo
• OTHER: Saline

Sponsor

GlaxoSmithKline

Collaborators

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