Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer
ACTIVE_NOT_RECRUITING
Status
Conditions
- Clinical Stage I Gastric Cancer AJCC v8
- Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8
- Clinical Stage II Gastric Cancer AJCC v8
- Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
- Clinical Stage III Gastric Cancer AJCC v8
- Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
- Clinical Stage IVA Gastric Cancer AJCC v8
- Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
- Gastric Adenocarcinoma
- Gastroesophageal Junction Adenocarcinoma
Interventions
- BIOLOGICAL: Atezolizumab
- PROCEDURE: Biospecimen Collection
- DRUG: Capecitabine
- PROCEDURE: Computed Tomography
- DRUG: Docetaxel
- PROCEDURE: Echocardiography Test
- DRUG: Fluorouracil
- DRUG: Leucovorin Calcium
- PROCEDURE: Lymphadenectomy
- PROCEDURE: Magnetic Resonance Imaging
- DRUG: Oxaliplatin
- PROCEDURE: Positron Emission Tomography
- PROCEDURE: Surgical Procedure
Sponsor
National Cancer Institute (NCI)