Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

NCT06102902 · clinicaltrials.gov ↗

PHASE1

Phase

SUSPENDED

Status

30

Enrollment

NIH

Sponsor class

Stopped Other - Pending amendment.

Conditions

Metastatic Colorectal Adenocarcinoma
Recurrent Colorectal Adenocarcinoma
Refractory Colorectal Adenocarcinoma
Stage IV Colorectal Cancer AJCC v8

Interventions

DRUG: BET Bromodomain Inhibitor ZEN-3694
PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
BIOLOGICAL: Cetuximab
PROCEDURE: Computed Tomography
PROCEDURE: Echocardiography Test
DRUG: Encorafenib
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Multigated Acquisition Scan

Sponsor

National Cancer Institute (NCI)