Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

NCT06126276 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

70

Enrollment

NIH

Sponsor class

Conditions

Malignant Female Reproductive System Neoplasm
Malignant Solid Neoplasm
Recurrent Malignant Female Reproductive System Neoplasm
Recurrent Malignant Solid Neoplasm

Interventions

PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
PROCEDURE: Echocardiography Test
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Multigated Acquisition Scan
DRUG: Neratinib Maleate
DRUG: Palbociclib

Sponsor

National Cancer Institute (NCI)