# Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG

> **NCT06221553** · PHASE1 · RECRUITING · sponsor: **Chulalongkorn University** · enrollment: 9 (estimated)

## Conditions studied

- DIPG Brain Tumor
- Diffuse Intrinsic Pontine Glioma

## Interventions

- **BIOLOGICAL:** B7H3 specific CAR T cell with IL-7Ra signaling domain

## Key facts

- **NCT ID:** NCT06221553
- **Lead sponsor:** Chulalongkorn University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-03-01
- **Primary completion:** 2026-03-01
- **Final completion:** 2026-09-01
- **Target enrollment:** 9 (ESTIMATED)
- **Last updated:** 2025-03-30

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06221553

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06221553, "Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPG". Retrieved via MORVS 2026-10-10 from https://api.morvs.ai/clinical/NCT06221553. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*