Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation

NCT06252870 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

82

Enrollment

OTHER

Sponsor class

Conditions

Graft Versus Host Disease
Hematologic Malignancy

Interventions

DRUG: Methotrexate
DRUG: Post-Transplant Cyclophosphamide
DRUG: Fludarabine
DRUG: Cycophosphamide
DRUG: Anti-Thymoglobulin
RADIATION: total body irradiation
OTHER: hematopoietic stem cells
OTHER: Graft nuclear cells
OTHER: Donor Lymphocytes Injection
DRUG: Clofarabine
DRUG: Thiotepa
DRUG: Busulfan
DRUG: Fludarabine

Sponsor

Nantes University Hospital