# Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy

> **NCT06278727** · — · UNKNOWN · sponsor: **Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University** · enrollment: 270 (estimated)

## Conditions studied

- Mitral Regurgitation
- Heart Failure

## Interventions

- **DRUG:** angiotensin-converting enzyme inhibitors/angiotensin II receptor blocker/angiotensin receptor-neprilysin inhibitor
- **OTHER:** The development of the prediction model

## Key facts

- **NCT ID:** NCT06278727
- **Lead sponsor:** Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** UNKNOWN
- **Start date:** 2024-01-01
- **Primary completion:** 2025-06-01
- **Final completion:** 2025-12-31
- **Target enrollment:** 270 (ESTIMATED)
- **Last updated:** 2024-02-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06278727

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06278727, "Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy". Retrieved via MORVS 2026-10-10 from https://api.morvs.ai/clinical/NCT06278727. Licensed CC0.

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