VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway

NCT06320951 · clinicaltrials.gov ↗

PHASE2

Phase

NOT_YET_RECRUITING

Status

200

Enrollment

OTHER

Sponsor class

Conditions

Cardiovascular Diseases
Insulin Sensitivity/Resistance
Metabolic Disease
Metabolism
Energy Expenditure
Obesity

Interventions

DRUG: Vericiguat 10 MG
OTHER: Placebo
OTHER: Insulin Sensitivity Test
OTHER: Resting Energy and Exercise Energy Expenditure Assessment
OTHER: White Adipose Tissue Biopsy
OTHER: MRI-PET Scan for Brown Adipose Tissue Volume Assessment

Sponsor

University of Alabama at Birmingham