Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

NCT06528691 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

52

Enrollment

OTHER

Sponsor class

Conditions

High Grade Glioma
CNS Tumor

Interventions

DRUG: Entrectinib
DRUG: Cyclophosphamide
DRUG: Etoposide
DRUG: Carboplatin
BIOLOGICAL: G-CSF
BIOLOGICAL: Pegfilgrastim
PROCEDURE: Surgery

Sponsor

St. Jude Children's Research Hospital

Collaborators

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