# Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

> **NCT06635980** · PHASE2 · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 120 (estimated)

## Conditions studied

- Anatomic Stage I Breast Cancer AJCC v8
- Anatomic Stage II Breast Cancer AJCC v8
- Anatomic Stage III Breast Cancer AJCC v8
- Breast Carcinoma
- Triple-Negative Breast Carcinoma

## Interventions

- **PROCEDURE:** Biopsy of Breast
- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Breast Surgery
- **DRUG:** Chemotherapy
- **PROCEDURE:** Computed Tomography
- **PROCEDURE:** Contrast Enhanced Digital Mammography
- **RADIATION:** Hypofractionated Radiation Therapy
- **PROCEDURE:** Magnetic Resonance Imaging
- **PROCEDURE:** Positron Emission Tomography
- **OTHER:** Survey Administration
- **PROCEDURE:** Tissue Collection
- **PROCEDURE:** Ultrasound Imaging

## Key facts

- **NCT ID:** NCT06635980
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-05-14
- **Primary completion:** 2031-10-21
- **Final completion:** 2034-10-21
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2025-12-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06635980

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06635980, "Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer". Retrieved via MORVS 2026-11-02 from https://api.morvs.ai/clinical/NCT06635980. Licensed CC0.

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