Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

NCT06696768 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

24

Enrollment

NIH

Sponsor class

Conditions

Metastatic Colorectal Adenocarcinoma
Stage III Colorectal Cancer AJCC v8
Stage IV Colorectal Cancer AJCC v8
Unresectable Colorectal Adenocarcinoma

Interventions

BIOLOGICAL: Bevacizumab
PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
BIOLOGICAL: Emavusertib
DRUG: Fluorouracil
DRUG: Leucovorin Calcium
PROCEDURE: Magnetic Resonance Imaging
DRUG: Oxaliplatin
PROCEDURE: Positron Emission Tomography

Sponsor

National Cancer Institute (NCI)