Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

NCT06738368 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

30

Enrollment

OTHER

Sponsor class

Conditions

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
T Acute Lymphoblastic Leukemia

Interventions

DRUG: Asparaginase Erwinia chrysanthemi
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Collection
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
DRUG: Doxorubicin
DRUG: Etoposide
BIOLOGICAL: Filgrastim
BIOLOGICAL: Pegfilgrastim
PROCEDURE: Positron Emission Tomography
DRUG: Prednisone
BIOLOGICAL: Rituximab
DRUG: Vincristine

Sponsor

University of Washington

Collaborators

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