Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

NCT06894979 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

54

Enrollment

NETWORK

Sponsor class

Conditions

Childhood Astrocytoma
Childhood Diffuse Intrinsic Pontine Glioma
Childhood Diffuse Midline Glioma
Childhood Glioblastoma
Childhood Malignant Glioma

Interventions

DRUG: ATM Kinase Inhibitor AZD1390
PROCEDURE: Biospecimen Collection
PROCEDURE: Magnetic Resonance Imaging
RADIATION: Radiation Therapy
OTHER: Survey Administration

Sponsor

Children's Oncology Group