Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)

NCT06912763 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

250

Enrollment

OTHER

Sponsor class

Conditions

Fibrosis Syndrome
Lymphedema
Head &Amp; Neck Cancer
Fibrosis

Interventions

DRUG: Pravastatin (drug)
DRUG: Pentoxifylline
DRUG: ketoprofen
DRUG: Pirfenidoneone
OTHER: Standard of Care (SOC)
DRUG: tocopherol

Sponsor

M.D. Anderson Cancer Center