A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

NCT07012044 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

47

Enrollment

NIH

Sponsor class

Conditions

Acute Myeloid Leukemia Post Cytotoxic Therapy
Recurrent Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia

Interventions

PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
DRUG: Decitabine
DRUG: Decitabine and Cedazuridine
BIOLOGICAL: Filgrastim
PROCEDURE: Imaging Procedure
PROCEDURE: Lumbar Puncture

Sponsor

National Cancer Institute (NCI)