# Dexmedetomidine as an Adjunct to Periarticular Ropivacaine in Total Knee Replacement: A Pilot Randomised Controlled Trial

> **NCT07176065** · PHASE4 · NOT_YET_RECRUITING · sponsor: **University of Malaya** · enrollment: 60 (estimated)

## Conditions studied

- Postoperative Pain Management in Total Knee Arthroplasty

## Interventions

- **DRUG:** Ropivacaine + saline solution
- **DRUG:** Ropivacaine + Dexmedetomidine

## Key facts

- **NCT ID:** NCT07176065
- **Lead sponsor:** University of Malaya
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2025-10
- **Primary completion:** 2027-12
- **Final completion:** 2028-12
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2025-09-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07176065

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07176065, "Dexmedetomidine as an Adjunct to Periarticular Ropivacaine in Total Knee Replacement: A Pilot Randomised Controlled Trial". Retrieved via MORVS 2026-10-12 from https://api.morvs.ai/clinical/NCT07176065. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*