CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

NCT07257419 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

70

Enrollment

OTHER

Sponsor class

Conditions

Relapsed Pediatric ALL
Hematopoietic Cell Transplantation
Hematologic Malignancy

Interventions

DRUG: Anti-Thymocyte Globulin (Rabbit)
DRUG: Cyclophosphamide
DRUG: Fludarabine
DRUG: Thiotepa
DRUG: Mesna
DRUG: Melphalan
DRUG: Filgrastim
DEVICE: CliniMACS System

Sponsor

St. Jude Children's Research Hospital