Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

NCT07281417 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

108

Enrollment

NIH

Sponsor class

Conditions

Sinonasal Squamous Cell Carcinoma
Stage III Sinonasal Cancer AJCC v8
Stage IVA Sinonasal Cancer AJCC v8
Stage IVB Sinonasal Cancer AJCC v8

Interventions

PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
DRUG: Carboplatin
DRUG: Carboplatin
BIOLOGICAL: Cemiplimab
OTHER: Chemoradiotherapy
DRUG: Cisplatin
PROCEDURE: Computed Tomography
PROCEDURE: Magnetic Resonance Imaging
DRUG: Paclitaxel
PROCEDURE: Positron Emission Tomography
RADIATION: Radiation Therapy
PROCEDURE: Surgical Procedure

Sponsor

National Cancer Institute (NCI)