Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+) or ABL-class Ph-like Acute Lymphoblastic Leukemia (ALL)

NCT07387926 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

NOT_YET_RECRUITING

Status

50

Enrollment

INDUSTRY

Sponsor class

Conditions

Acute Lymphoblastic Leukemia
Leukemia, Lymphoblastic, Acute, Philadelphia-Positive
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Interventions

DRUG: Asciminib Adult formulation
DRUG: Asciminib Pediatric formulation
DRUG: Dexamethasone
DRUG: Vincristine
DRUG: Blinatumomab
DRUG: Methotrexate (intrathecal)
DRUG: Cytarabine (intrathecal)
DRUG: Hydrocortisone (intrathecal)
DRUG: Prednisolone (intrathecal)

Sponsor

Novartis Pharmaceuticals