Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) for Previously Untreated Mantle Cell Lymphoma

NCT07444710 · clinicaltrials.gov ↗

PHASE1

Phase

NOT_YET_RECRUITING

Status

16

Enrollment

NIH

Sponsor class

Conditions

Ann Arbor Stage II Mantle Cell Lymphoma
Ann Arbor Stage III Mantle Cell Lymphoma
Ann Arbor Stage IV Mantle Cell Lymphoma

Interventions

PROCEDURE: Biospecimen Collection
DRUG: Cisplatin
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
DRUG: Cytarabine
DRUG: Dexamethasone
DRUG: Doxorubicin
BIOLOGICAL: Glofitamab
PROCEDURE: Positron Emission Tomography
DRUG: Prednisone
BIOLOGICAL: Rituximab
DRUG: Vincristine

Sponsor

National Cancer Institute (NCI)