# Left Atrial Appendage Closure With Versus Without Pulsed Field Ablation in Atrial Fibrillation Patients With Mild Symptoms and High Stroke Risk

> **NCT07453940** · NA · RECRUITING · sponsor: **Sir Run Run Shaw Hospital** · enrollment: 50 (estimated)

## Conditions studied

- ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION
- PFA Ablation and LAAC Procedures

## Interventions

- **PROCEDURE:** LAAC plus PFA for persistent AF with high risk of stroke
- **PROCEDURE:** LAAC for persistent AF with high risk of stroke

## Key facts

- **NCT ID:** NCT07453940
- **Lead sponsor:** Sir Run Run Shaw Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-04-01
- **Primary completion:** 2026-12-15
- **Final completion:** 2027-01-31
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2026-03-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07453940

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07453940, "Left Atrial Appendage Closure With Versus Without Pulsed Field Ablation in Atrial Fibrillation Patients With Mild Symptoms and High Stroke Risk". Retrieved via MORVS 2026-10-17 from https://api.morvs.ai/clinical/NCT07453940. Licensed CC0.

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