# International Multi-center Retrospective Study of Patients With Serum Sodium ≤110 mmol/L to Determine the Relationship Between Osmotic Demyelination Syndrome (ODS) and Rapid Correction of Hyponatremia

> **NCT07576036** · — · ENROLLING_BY_INVITATION · sponsor: **Rochester General Hospital** · enrollment: 800 (estimated)

## Conditions studied

- Hyponatremia Symptomatic
- Osmotic Demyelination Syndrome
- Cerebral Edema

## Interventions

- **DRUG:** Hypertonic 3% saline

## Key facts

- **NCT ID:** NCT07576036
- **Lead sponsor:** Rochester General Hospital
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2023-11-01
- **Primary completion:** 2026-06-30
- **Final completion:** 2026-06-30
- **Target enrollment:** 800 (ESTIMATED)
- **Last updated:** 2026-05-08

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07576036

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07576036, "International Multi-center Retrospective Study of Patients With Serum Sodium ≤110 mmol/L to Determine the Relationship Between Osmotic Demyelination Syndrome (ODS) and Rapid Correction of Hyponatremia". Retrieved via MORVS 2026-10-16 from https://api.morvs.ai/clinical/NCT07576036. Licensed CC0.

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