Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis
Conditions
- Anatomic Stage IV Breast Cancer AJCC v8
- Metastatic HER2-Positive Breast Carcinoma
- Oligometastatic Breast Carcinoma
Interventions
- PROCEDURE: Biopsy Procedure
- PROCEDURE: Biospecimen Collection
- PROCEDURE: Breast Conservation Treatment
- PROCEDURE: Computed Tomography
- DRUG: Cyclin-Dependent Kinase 4 Inhibitor
- DRUG: Cyclin-Dependent Kinase 6 Inhibitor
- PROCEDURE: Echocardiography Test
- DRUG: HER2-targeted Therapy
- DRUG: Hormone Therapy
- PROCEDURE: Magnetic Resonance Imaging
- PROCEDURE: Mammography
- BIOLOGICAL: Pertuzumab
- PROCEDURE: Positron Emission Tomography
- RADIATION: Radiation Boost
- RADIATION: Radiation Therapy
- RADIATION: Stereotactic Body Radiation Therapy
- RADIATION: Stereotactic Radiosurgery
- DRUG: Taxane Compound
- PROCEDURE: Total Mastectomy
- BIOLOGICAL: Trastuzumab
Sponsor
SWOG Cancer Research Network
Collaborators