Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN)

Conditions

• Severe Mental Illness
• Depression / Major Depressive Disorder
• Bipolar Disorder (BD)
• Schizophrenia

Interventions

• DRUG: Semaglutide (SEMA)
• BEHAVIORAL: Exercise module
• BEHAVIORAL: Anti-inflammatory diet module
• BEHAVIORAL: Sleep intervention module
• BEHAVIORAL: Social prescribing module
• DEVICE: Closed-loop transcranial alternating current stimulation (CL-tACS)
• BEHAVIORAL: Structured lifestyle psychoeducation
• DEVICE: Sham CL-tACS

Sponsor

Ludwig-Maximilians - University of Munich