# Complementary Herbal Approach to Rheumatoid Management Study (CHARMS)

> **NCT07627893** · PHASE2,PHASE3 · RECRUITING · sponsor: **Singapore General Hospital** · enrollment: 132 (estimated)

## Conditions studied

- Rheumatoid Arthritis (RA)

## Interventions

- **OTHER:** Shu Bi Ning (modified Si Miao Xiao Bi)
- **DRUG:** Methotrexate
- **OTHER:** Shu Bi Ning placebo

## Key facts

- **NCT ID:** NCT07627893
- **Lead sponsor:** Singapore General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-06-01
- **Primary completion:** 2029-05-31
- **Final completion:** 2030-06-30
- **Target enrollment:** 132 (ESTIMATED)
- **Last updated:** 2026-08-17

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07627893

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07627893, "Complementary Herbal Approach to Rheumatoid Management Study (CHARMS)". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07627893. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*