# STEPwise De-escalation and Optimizing Withdrawal of ARNI and SGLT2i in Normalized Heart Failure

> **NCT07631156** · PHASE4 · RECRUITING · sponsor: **Kyungsub Song** · enrollment: 80 (estimated)

## Conditions studied

- Heart Failure With Reduced Ejection Fraction
- Heart Failure
- Ventricular Dysfunction, Left

## Interventions

- **DRUG:** Stepwise Withdrawal of ARNI and SGLT2i
- **DRUG:** Continued Guideline-Directed Medical Therapy

## Key facts

- **NCT ID:** NCT07631156
- **Lead sponsor:** Kyungsub Song
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-08-12
- **Primary completion:** 2029-06-30
- **Final completion:** 2029-12-30
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2026-09-02

## Collaborators

- [object Object]
- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07631156

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07631156, "STEPwise De-escalation and Optimizing Withdrawal of ARNI and SGLT2i in Normalized Heart Failure". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07631156. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*